Afinitor (Everolimus)

Afinitor
Everolimus

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Afinitor Disperz
Everolimus

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Zortress
Everolimus

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Afinitor
Everolimus

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Generic Equivalents   What's the difference?
Everolimus
Everolimus

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Afinitor (Everolimus) is a prescription medication approved for use in treating various types of cancer and tumors. It belongs to a class of drugs known as mTOR inhibitors, which work by interfering with cellular signaling pathways that promote cell division and growth.

Why Choose Afinitor (Everolimus)?

 

  • Targeted Therapy: Afinitor specifically targets the mTOR pathway, a crucial player in cell growth and proliferation, making it an effective treatment for certain cancers.
  • Versatile Treatment Options: Approved for various conditions including advanced renal cell carcinoma, progressive neuroendocrine tumors of pancreatic origin, and advanced hormone receptor-positive, HER2-negative breast cancer.
  • Proven Efficacy: Demonstrated in clinical trials to slow the progression of certain cancers and improve survival rates in some patient populations.

How to Use Afinitor (Everolimus)?

 

  • Understand Your Prescription: Know the dose prescribed and the conditions under which it should be taken. Confirm the frequency and timing of the doses.
  • Consistent Timing: Take Afinitor at the same time every day to maintain an even level of medication in your body.
  • With or Without Food: Afinitor can be taken with or without food. However, it’s important to be consistent in the way you take it—either always with food or always without.
  • Swallow Whole: Swallow the tablets whole with a glass of water. Do not chew or crush the tablets.
  • Handling Precautions: If you accidentally break a tablet, avoid inhaling the powder or letting it come into contact with your skin or mucous membranes.

Important Safety Information about Afinitor

 

  • Monitor for Infections: Be alert for signs of infections, such as fever or increased fatigue. Afinitor can lower your ability to fight infections.
  • Regular Medical Follow-ups: Attend all scheduled appointments with your healthcare provider. Your treatment and condition need to be monitored regularly.
  • Avoid Live Vaccines: Consult with your doctor before receiving any vaccines, as live vaccines may not be advisable during treatment with Afinitor.
  • Limit Exposure to Sunlight: Afinitor may make your skin more sensitive to sunlight. Wear protective clothing and use sunscreen when outdoors.

Fact Table for Afinitor

 

Facts Details
Generic Name Everolimus
Brand Name Afinitor
Drug Class mTOR inhibitor (mechanistic target of rapamycin inhibitor)
FDA Approved Yes
Indications – Advanced renal cell carcinoma (RCC )- Progressive neuroendocrine tumors of pancreatic origin (PNET) – Advanced hormone receptor-positive, HER2-negative breast cancer in postmenopausal women – Subependymal giant cell astrocytoma (SEGA) – Renal angiomyolipoma and tuberous sclerosis complex (TSC)
Administration Oral
Dosage Form Tablets
Common Side Effects – Mouth ulcers – Infections – Fatigue – Diarrhea – Decreased appetite – Inflammation of lung tissue- Abnormal taste sensation – Weight loss
Contraindications – Hypersensitivity to everolimus or other rapamycin derivatives
Interactions – Strong inhibitors or inducers of CYP3A4 and P-gp
Precautions – Monitor for infections – Regular blood work for kidney function, blood sugar, and cholesterol levels
Usage Instructions – Take at the same time each day – Can be taken with or without food- Swallow tablets whole
Storage Instructions – Store at room temperature – Keep container tightly closed

 

Common Side Effects of Afinitor

Like all medications, Afinitor (Everolimus) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

  • Mouth ulcers
  • Infections
  • Fatigue
  • Diarrhea
  • Decreased appetite

If you experience any of these side effects or others, make sure to discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Afinitor (Everolimus)?

You can order Afinitor (Everolimus) using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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