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Humira (Adalimumab)
Humira (adalimumab) is a prescription medication that is used to treat a variety of chronic inflammatory conditions. As a TNF-alpha inhibitor, Humira works by reducing inflammation and slowing the progression of disease in conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn’s disease, ulcerative colitis, and plaque psoriasis.
Why Choose Humira (Adalimumab)?
- Reduces signs and symptoms of inflammatory conditions.
- Can help maintain day-to-day functionality.
- May provide significant relief from pain and discomfort.
- Helps slow the progression of joint damage in rheumatoid arthritis.
How to Use Humira (Adalimumab)?
- Preparation: Allow Humira to warm to room temperature for 15 to 30 minutes before injecting. This helps reduce discomfort from the injection. Do not heat Humira in any other way (e.g., do not warm it in a microwave or in hot water).
- Choose an injection site: Suitable sites for injection include the front of your thighs or the lower abdomen, at least two inches away from the belly button. Rotate the injection site with each injection to avoid skin problems.
- Clean the injection site: Use an alcohol wipe to clean the skin where you will inject Humira. Allow the skin to dry naturally.
- Prepare the syringe or pen: If using a syringe, remove the cap and hold the syringe by the barrel. If using an auto-injector (pen), remove the cap and follow the specific instructions for the device.
- Inject the medication: Pinch the skin lightly and insert the needle at about a 45-degree angle. If using a syringe, push the plunger slowly and steadily until all the medication is injected. If using a pen, press the button and hold for 10 seconds after you hear a click to make sure all medication is delivered.
- Dispose of the needle: Immediately place used needles and syringes into an FDA-cleared sharps disposal container. Do not throw them into household trash.
Important Safety Information about Humira
- Check the medication: Ensure that the liquid in the Humira pre-filled syringe or pen is clear and colorless to pale yellow. Do not use it if the liquid is cloudy, discolored, or has particles in it.
- Check the injection site: There might be slight bleeding. Press a cotton ball or gauze over the area if needed. Do not rub the injection site.
- Observe for reactions: Watch for signs of injection site reactions such as redness, swelling, or pain. These are usually mild and clear up within a few days. Seek medical advice if they persist or worsen.
- Storage: Store Humira in the refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Keep it in the original carton to protect it from light until the time of use.
Fact Table for Humira
| Facts | Details |
| Generic Name | Adalimumab |
| Brand Name | Humira |
| Drug Type | Biologic; TNF-alpha inhibitor |
| FDA Approval | Initially approved in 2002 |
| Indications | – Rheumatoid Arthritis – Psoriatic Arthritis- Ankylosing Spondylitis – Crohn’s Disease – Ulcerative Colitis – Plaque Psoriasis – Juvenile Idiopathic Arthritis |
| Administration | Subcutaneous injection |
| Dosage Form | Pre-filled syringe or auto-injector pen |
| Recommended Dose | Varies by condition, typically starting with a loading dose followed by a maintenance dose |
| Mechanism of Action | Inhibits tumor necrosis factor-alpha (TNF-alpha), a substance in the body that causes inflammation |
| Contraindications | – Known hypersensitivity to adalimumab or any Humira components – Active tuberculosis or other severe infections |
| Common Side Effects | – Injection site reactions (pain, redness, swelling) – Upper respiratory infections – Headaches – Nausea |
| Special Considerations | – Requires refrigeration (2°C to 8°C)- Patients should be tested for TB before starting treatment – Regular monitoring for signs of infection |
| Storage | Store in a refrigerator at 2°C to 8°C; protect from light; do not freeze |
Common Side Effects of Humira
Like all medications, Humira (Adalimumab) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Injection site reactions
- Upper respiratory infections
- Headaches
- Nausea
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Humira (Adalimumab)?
You can order Humira (Adalimumab) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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