Lynparza (Olaparib)

Lynparza
Olaparib

Source:
Source:
Lynparza
Olaparib

Source:
Source:

Lynparza (Olaparib) is designed specifically for the management of specific gene-mutated cancers. Approved by major health authorities, it is a targeted therapy known as a PARP inhibitor, used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer in patients with specific genetic profiles.

Why Choose Lynparza (Olaparib)?

  • Specifically targets and inhibits PARP enzymes, crucial for DNA repair in cancer cells, leading to cell death and potentially slowing the spread of cancer.
  • Offers a personalized treatment approach by targeting cancers based on genetic makeup.
  • Demonstrated improvement in progression-free survival in several clinical trials across different indications.

How to Use Lynparza (Olaparib)?

  • Dosage: Lynparza is prescribed at a dose recommended by your oncologist, often taken as tablets twice daily.
  • Administration: Swallow the tablets whole with water. They can be taken with or without food, but try to take them at the same times every day to maintain an even level of the medication in your body.
  • Duration of Treatment: Continue taking Lynparza as directed by your doctor. Do not stop or alter the dosage without consulting your healthcare provider, even if you feel well.
  • Monitoring: Regular appointments will be necessary to monitor your response to Lynparza and adjust the treatment as needed. Blood tests, scans, and other evaluations may be part of your treatment plan to check for side effects and monitor your overall health.

Important Safety Information about Lynparza

  • Pregnancy and Breastfeeding: Avoid using Lynparza if you are pregnant, as it can harm the fetus. Both women and men using Lynparza should use effective contraception during treatment and for some time after the last dose. Do not breastfeed during treatment and for some time after the last dose.
  • Drug Interactions: Inform your healthcare provider about all other medications you are taking, as Lynparza can interact with other drugs, potentially affecting how well it or the other medicines work.
  • Elderly: Older adults may be more sensitive to the side effects of the drug, particularly bone marrow suppression and gastrointestinal effects.
  • Kidney Problems: Patients with pre-existing kidney issues should discuss the use of Lynparza with their doctor, as dose adjustments may be necessary.

Fact Table for Lynparza

Facts Details
Generic Name Olaparib
Brand Name Lynparza
Drug Class PARP inhibitor
FDA Approval Yes, for specific cancer types with genetic mutations
Indications Ovarian, breast, pancreatic, and prostate cancers with specific genetic mutations
Dosage Form Oral tablets
Common Dosage 300 mg taken twice daily
Administration Taken with or without food
Primary Side Effects Nausea, fatigue, anemia, vomiting, diarrhea, decreased appetite, headache
Contraindications Pregnancy (can cause fetal harm), severe renal impairment unmonitored
Drug Interactions Sensitive to CYP3A inhibitors/inducers and certain other medications
Use in Special Populations Caution is advised in patients with severe renal impairment or those who are elderly
Mechanism of Action Inhibits PARP enzymes, leading to DNA damage in cancer cells and cell death
Effectiveness Shown to improve progression-free survival in several clinical trials across different indications
Monitoring Requirements Regular blood tests, monitoring for signs of lung problems, and other cancer screenings
Precautions Use effective contraception during treatment and for some time after completion

 

Common Side Effects of Lynparza

Like all medications, Lynparza (Olaparib) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

  • Nausea
  • Fatigue
  • Vomiting
  • Diarrhea
  • Decreased appetite

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Lynparza (Olaparib)?

You can order Lynparza (Olaparib) using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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