Megace (Megestrol Acetate)

Generic Equivalents   What's the difference?
Megestrol
Megestrol Acetate

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Megace (Megestrol Acetate) is a potent, oral synthetic progestin widely used in the treatment of advanced breast cancer and endometrial cancer. It is also effectively employed for appetite stimulation and weight gain in patients with AIDS and cancer.

Why Choose Megace (Megestrol Acetate)?

  • Targeted Cancer Treatment: Especially beneficial in the management of hormone-responsive breast cancer and endometrial cancer, helping to slow or stop the growth of cancer cells.
  • Appetite Enhancement: Clinically proven to increase appetite, which is crucial in aiding patients who suffer from severe weight loss due to cancer or AIDS.
  • Ease of Use: Available in two convenient forms, oral suspension, and tablets, offering flexibility and ease of administration.
  • Well-Studied: Supported by extensive clinical research and studies, affirming its efficacy and safety profile in its approved uses.

How to Use Megace (Megestrol Acetate)?

  • The dosage of Megace varies significantly based on the individual patient’s condition, weight, and the severity of symptoms. The medication is typically taken once daily, but specific instructions will be provided by the healthcare provider.
  • Follow the dosing schedule strictly as prescribed by your doctor, without skipping doses or discontinuing treatment unless advised.
  • If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and resume your regular dosing schedule.
  • Store at room temperature away from moisture and heat. Keep out of reach of children.

Important Safety Information about Megace

  • Contraindicated in pregnant women due to potential harm to the fetus.
  • Patients with a history of thromboembolic disease should be used with caution.
  • Regular follow-ups and lab tests may be required to monitor your condition and check for side effects.

Fact Table for Megace (Megestrol Acetate)

Facts Details
Generic Name Megestrol Acetate
Brand Name(s) Megace®, Megace ES®
Drug Class Progestin, Appetite Stimulant
FDA Approval Approved for the treatment of advanced breast cancer, endometrial cancer, anorexia, cachexia, and unexplained significant weight loss in AIDS patients.
Formulation Oral suspension (40 mg/mL), Tablets (20 mg, 40 mg)
Administration Route Oral
Typical Dosage Varies based on condition and patient response. Commonly: 40-320 mg/day in divided doses for cancer; 800 mg/day for anorexia or cachexia.
Usage As prescribed by a healthcare professional, taken once daily or as directed.
Common Side Effects Increased appetite, weight gain, nausea, vomiting, hypertension, hyperglycemia, mild rash, itching.
Contraindications Pregnancy, known hypersensitivity to megestrol acetate or any component of the formulation.
Precautions Use caution in patients with a history of thromboembolic disease, diabetes, or adrenal insufficiency. Regular monitoring for side effects and efficacy.
Interactions Can interact with certain medications including insulin or oral diabetes drugs, blood thinners.
Storage Store at room temperature, away from moisture and heat. Keep out of reach of children.

 

Common Side Effects Megace

Like all medications, Megace (Megestrol Acetate) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

  • Increased appetite
  • Weight gain
  • Stomach upset
  • Mild rash
  • Itching
  • Deep vein thrombosis
  • Pulmonary embolism
  • Hypertension
  • Hyperglycemia

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Megace (Megestrol Acetate)?

You can order Megace using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

 

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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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