Sinemet CR (Carbidopa/Levodopa)
Sinemet CR is a cutting-edge drug that relieves the symptoms of Parkinson’s disease and Parkinsonism. Sinemet CR, a combination of Carbidopa and Levodopa, addresses the neurological root of the disorder, allowing patients to improve their mobility and quality of life. Our extended-release composition guarantees that the medication is released steadily throughout the day, giving unchanged symptom control.
Why Choose Sinemet CR (Carbidopa/Levodopa)?
- Improved Mobility: Helps to restore balance and control over movements, minimizing tremors and stiffness.
- Extended Relief: Specifically developed to give long-term symptom control, eliminating the need for regular doses.
- Improved Quality of Life: By efficiently treating symptoms, patients can engage in daily activities with less interruption from their disease.
How to Use Sinemet CR (Carbidopa/Levodopa)?
- Consult your doctor: Begin by consulting with your healthcare professional to establish whether Sinemet CR is appropriate for you, taking into account your medical history, other prescriptions, and overall health.
- Follow the Prescribed Dosage: Your doctor will determine the proper dosage and schedule depending on your unique condition and response to therapy. It is critical to follow these directions properly.
- Consistent Intake: Take your prescription at the same times every day to ensure an even level of medication in your body.
- Whole Tablets: Swallow the extended-release pills whole. Do not crush, chew, or break the tablets because this can alter how the drug is delivered and absorbed.
- With or Without Food: Sinemet CR may be taken with or without food. However, taking it with food can reduce nausea, which is a typical adverse effect. Maintain consistency in how you approach food.
- Dose Adjustments: Your doctor may alter your dose based on how you respond to the drug and any side effects you experience. Never change the dosage yourself.
Important Safety Information about Sinemet CR
- Allergies: Do not take Sinemet CR if you are allergic to carbidopa, levodopa, or any of the medication’s ingredients.
- Certain Medical Conditions: Patients with narrow-angle glaucoma, hormonal problems, or a history of melanoma should exercise caution.
- Medical History: Tell your doctor about your entire medical history, including any heart disease, liver disease, renal illness, respiratory diseases, or psychiatric issues.
- Other medications: All medications you use, including prescriptions, over-the-counter medications, and herbal supplements, should be mentioned because they may interact with Sinemet CR.
- Pregnancy and Breastfeeding: If you are pregnant, plan to become pregnant, or are breastfeeding, talk to your doctor about the risks and benefits.
Fact Table for Sinemet CR
| Facts | Details |
| Generic Name | Carbidopa/Levodopa |
| Brand Name | Sinemet CR |
| Classification | Antiparkinson Agent |
| FDA Approval | Yes |
| Form | Extended-Release Tablet |
| Prescription Required | Yes |
| Indication | Used to treat symptoms of Parkinson’s disease and Parkinson’s disease symptoms caused by other conditions. |
| How It Works | Levodopa is converted to dopamine in the brain, helping to control movement. Carbidopa prevents levodopa from breaking down before it reaches the brain. |
| Dosage Form | Extended-release tablets are available in different strengths (e.g., 25/100 mg, 50/200 mg of Carbidopa/Levodopa). |
| Administration | Orally, with or without food. The tablets should not be crushed, chewed, or split. |
| Common Side Effects | Nausea, dizziness, insomnia, dry mouth, orthostatic hypotension. |
| Use in Specific Populations | Caution in patients with glaucoma, severe cardiovascular or pulmonary disease, renal or hepatic impairment. Discuss use during pregnancy and breastfeeding with a healthcare provider. |
| Drug Interactions | Can interact with MAO inhibitors, antihypertensive drugs, antipsychotics, and others. Always inform healthcare providers about all medications being taken. |
| Special Considerations | Avoid sudden discontinuation to prevent withdrawal symptoms. Dosage adjustments may be necessary based on effectiveness and tolerance. Regular monitoring by a healthcare provider is recommended. |
Common Side Effects of Sinemet CR
Like all medications, Sinemet CR (Carbidopa/Levodopa) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Nausea
- Dizziness
- Insomnia
- Dry mouth
- Changes in blood pressure
If you experience any of these side effects or others, make sure to discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Sinemet CR (Carbidopa/Levodopa)?
You can order Sinemet CR (Carbidopa/Levodopa) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
Please call 1-800-258-0477 or email us if you have any questions or concerns.
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