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Trexall (Methotrexate Sodium)
Trexall™ (Methotrexate Sodium) is a prescription medication for treating cancer, severe psoriasis, and adult rheumatoid arthritis. Methotrexate belongs to a class of medications known as antimetabolites, which function by slowing or preventing cancer cell development while blocking the immune system.
Why Choose Trexall (Methotrexate Sodium)?
- Effective Management of Rheumatoid Arthritis: Rheumatoid arthritis can be effectively managed by reducing pain and swelling.
- Psoriasis Relief: Helps to manage the symptoms of scaling and thickness of psoriasis, enhancing overall skin health.
- Cancer Treatment: Breast cancer, leukemia, and lung cancer are all treated with this drug as part of a chemotherapy regimen.
How to Use Trexall (Methotrexate Sodium)?
- Trexall dose is highly personalized and is decided depending on your medical condition, reaction to treatment, and, in the case of cancer treatment, specialized protocols incorporating other chemotherapy medicines.
- Always take Trexall exactly as directed by your doctor.
- Trexall is normally given orally in tablet form.
- Tablets should be eaten whole with water, not chewed or broken.
- It is essential to stick to the plan prescribed by your doctor, which can vary from once a week for illnesses such as arthritis or psoriasis to more specific schedules for treatment for cancer.
- Methotrexate is typically given once a week, rather than daily, for conditions such as rheumatoid arthritis and psoriasis. To avoid severe adverse effects, do not exceed the authorized dose or frequency.
- Take your medication on the same day every week to help you remember.
Important Safety Information about Trexall
- Blood Monitoring: Frequent blood tests are required to monitor your blood cells, as well as kidney and liver function.
- Avoid alcohol: Alcohol may raise the risk of liver disease. Avoid alcoholic drinks.
- Sun Exposure: Methotrexate may increase your sensitivity to sunlight. When spending time outside, limit your sun exposure and wear protective gear and sunscreen.
- Storage: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Fact Table for Trexall
| Facts | Details |
| Generic Name | Methotrexate Sodium |
| Brand Name | Trexall |
| Classification | Antimetabolite, Disease-Modifying Antirheumatic Drug (DMARD) |
| FDA Approval | Yes |
| Indications | – Rheumatoid arthritis – Psoriasis – Certain types of cancer (e.g., breast, lung, head and neck, and leukemia) |
| Dosage Forms | Tablet (available in various strengths, e.g., 5 mg, 7.5 mg, 10 mg, 15 mg) |
| Administration | Oral |
| Mechanism of Action | Inhibits dihydrofolate reductase, leading to a decrease in DNA synthesis and cellular replication |
| Key Side Effects | – Nausea and vomiting – Stomatitis – Hepatotoxicity- Bone marrow suppression – Pulmonary toxicity |
| Warnings and Precautions | – Contraindicated in pregnancy due to potential teratogenic effects – Regular monitoring of liver function, renal function, and blood cell counts is necessary – Avoid in patients with pre-existing blood dyscrasias or severe renal impairment |
| Drug Interactions | – NSAIDs – Antibiotics (e.g., penicillins, tetracyclines) – Oral antidiabetic drugs – Live vaccines |
| Storage | Store at room temperature away from moisture and direct light |
| Prescribing Information | Requires monitoring for toxicity, especially hepatic, hematologic, and pulmonary |
Common Side Effects of Trexall
Like all medications, Trexall (Methotrexate Sodium) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Nausea
- Vomiting
- Dizziness
- Mouth sores
If you experience any of these side effects or others, make sure to discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Trexall (Methotrexate Sodium)?
You can order Trexall (Methotrexate Sodium) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
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