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Welchol (Colesevelam Hydrochloride)
Welchol® is a prescription medication used to lower cholesterol levels and enhance glycemic control in adults. Welchol®, a bile acid sequestrant, acts by binding bile acids in the intestines hence reducing the amount of cholesterol absorbed from the food.
Why Choose Welchol (Colesevelam Hydrochloride)?
- Lowers LDL cholesterol: Welchol® effectively lowers bad cholesterol (LDL) levels, potentially lowering the risk of heart disease and stroke.
- Helps blood sugar control: When combined with diet and exercise, this drug can help persons with type 2 diabetes improve their glycemic control.
- Flexible dosing: Welchol® is available in tablet and oral suspension form, allowing for flexible administration based on patient preference.
How to Use Welchol (Colesevelam Hydrochloride)?
- Dosage: The normal dose is 3-6 tablets per day, given all at once or in divided doses. The oral suspension should be combined with either water, fruit juice, or diet soda.
- Administration: Welchol® pills should be taken with food and enough of drink to ensure proper consumption.
Important Safety Information about Welchol
- Allergies: Patients who are allergic to any of the compounds in Welchol® should not take this medication.
- Precautions: Exercise caution in people with gastrointestinal motility issues. Welchol® may interfere with the absorption of certain vitamins and other drugs.
- Pregnancy: If you are pregnant or plan to become pregnant, consult with your healthcare provider.
Fact Table for Welchol
| Facts | Details |
| Generic Name | Colesevelam Hydrochloride |
| Brand Name | Welchol |
| Classification | Bile acid sequestrant |
| FDA Approved Uses | – Reducing cholesterol levels in adults with primary hyperlipidemia. – Managing blood sugar levels in adults with type 2 diabetes. |
| Administration Form | – Oral tablets – Oral Suspension |
| Dosage Forms | – 625 mg tablets – Oral suspension powder |
| Typical Dosage | – 3.75 grams per day, typically divided into 2 doses |
| Mechanism of Action | Binds bile acids in the intestine, reducing their reabsorption and lowering cholesterol levels. |
| Common Side Effects | – Constipation – Indigestion – Nausea |
| Contraindications | – History of bowel obstruction – Serum triglyceride levels over 500 mg/dL (can increase levels) |
| Drug Interactions | – Welchol can decrease the absorption of certain medications (e.g., thyroid hormones, certain vitamins) |
| Monitoring Parameters | – Lipid levels – Blood glucose levels (for diabetics) – Liver function tests |
| Storage Recommendations | Store at room temperature, away from moisture and heat. |
| Regulatory Status | FDA-approved |
Common Side Effects of Welchol
Like all medications, Welchol (Colesevelam Hydrochloride) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Constipation
- Indigestion
- Nausea
If you experience any of these side effects or others, make sure to discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Welchol (Colesevelam Hydrochloride)?
You can order Welchol (Colesevelam Hydrochloride) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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