Zonegran (Zonisamide)

Zonegran
Zonisamide

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Generic Equivalents   What's the difference?
Zonisamide
Zonisamide

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Zonegran (Zonisamide) is a prescription medication used as an additional therapy to treat partial seizures in individuals with epilepsy. With Zonegran, you can live a more balanced life and have fewer seizures. Zonegran’s unique formulation is intended to supplement your current epilepsy treatment strategy, providing an extra layer of support to those seeking improved seizure control.

Why Choose Zonegran (Zonisamide)?

  • Effective Seizure Control: Zonegran has been clinically shown to lower the frequency of partial seizures in adults.
  • Once-Daily Dosing: Once-day dosing is convenient and fits readily into your daily schedule, promoting consistent drug adherence.
  • Complementary Therapy: Can be combined with other seizure drugs to improve seizure control.
  • Well-Tolerated: Zonegran is well-tolerated and has few side effects, making it an excellent supplement to your epilepsy treatment regimen.

How to Use Zonegran (Zonisamide)?

  • Zonegran is available in capsule form and should be taken once a day, with or without food.
  • A healthcare expert should determine dosage and administration depending on individual therapeutic response and tolerance.
  • To maintain optimal levels of the drug in your system, it is recommended that you take it every day at the same time.

Important Safety Information about Zonegran

  • Zonegran is not suitable for everyone. Give to the doctor your complete medical history, including any history of kidney stones, metabolic acidosis, or sensitivities to sulfonamide drugs.
  • Do not stop taking Zonegran without first consulting your doctor, as abrupt cessation may raise the risk of seizures.
  • Due to the potential hazards to the fetus or newborn, pregnant or nursing women should only use Zonegran with the supervision of a healthcare provider.

Fact Table for Zonegran

Facts Details
Generic Name Zonisamide
Brand Name Zonegran
Classification Anticonvulsant/Sulfonamide antiepileptic
FDA Approval Year 2000 for adults, Extended use for pediatric patients (age 6 and older) approved in 2011
Indications Used in combination with other medications to treat partial seizures in adults and children aged 6 and older with epilepsy.
Dosage Forms Capsule (25 mg, 50 mg, 100 mg)
Administration Route Oral
Mechanism of Action Though not fully understood, Zonisamide is thought to stabilize electrical activity in the brain by blocking sodium and calcium channels, which helps to reduce epileptic seizures.
Half-life Approximately 63 hours
Side Effects Common: drowsiness, dizziness, headache, loss of appetite, nausea.
Precautions Should not be used in patients with a history of hypersensitivity to sulfonamides. Caution in patients with renal or hepatic impairment, and those with a history of kidney stones.
Pregnancy Category Category C (Risk not ruled out). Animal studies have shown an adverse effect, but there are no adequate studies in pregnant women.
Interactions Can interact with other anticonvulsants, carbonic anhydrase inhibitors, alcohol, and drugs that are metabolized by the liver.
Storage Instructions Store at room temperature, away from direct light, moisture, and heat. Do not store in the bathroom. Keep all medications away from children and pets.

 

Common Side Effects of Zonegran

Like all medications, Zonegran (Zonisamide) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

  • Drowsiness
  • Dizziness
  • Headache

If you experience any of these side effects or others, make sure to discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Zonegran (Zonisamide)?

You can order Zonegran (Zonisamide) using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

 

Visit our How to order page.

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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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