Linzess can generally be taken concurrently with other medications without significant interactions or safety concerns. However, it’s important to avoid specific laxatives like magnesium citrate, sodium phosphate, and polyethylene glycol while using Linzess, as they may heighten the risk of experiencing diarrhea. For a more comprehensive understanding of Linzess, including its potential side effects, appropriate dosage, precautions, and indications, it is advisable to consult your doctor.